Distinct mechanisms of ER stress-mediated autophagy induction by high- and low-virulence pseudorabies virus strains

Key Points

• Autophagy induction is distinct between high- and low-virulence pseudorabies virus strains, signaling important differences.
• The study identifies critical mechanisms involved in ER stress that lead to varying autophagy responses.
• Analysis of virus strains shows how pathogenicity affects cellular processes, influencing the immune response.
• Findings may enable targeted strategies in disease management to tackle different virulence levels in viruses.