Association of plasma matrix metalloproteinase-9 and osteopontin levels with Apolipoprotein E genotypes of patients with mild cognitive impairment and Alzheimer’s disease | Synapse
March 3, 2026
Association of plasma matrix metalloproteinase-9 and osteopontin levels with Apolipoprotein E genotypes of patients with mild cognitive impairment and Alzheimer’s disease
Puntos clave
Increased plasma matrix metalloproteinase-9 levels correlate with Alzheimer's disease severity and cognitive decline.
Statistical analysis revealed significant differences in osteopontin levels among different Apolipoprotein E genotypes.
Assessment involved a comparative observational analysis of patients diagnosed with mild cognitive impairment and Alzheimer's disease.
Findings highlight potential biomarkers for disease progression and genetic risk factors in neurodegenerative disorders.