Establishment of measurement system for KLHL11 antibodies in Japan, and results of measurement in a large number of autoimmune cerebellar ataxia patients

Key Points

• KLHL11 antibodies were successfully measured in a significant number of autoimmune cerebellar ataxia patients, providing valuable diagnostic data.
• The study measured KLHL11 antibodies in over 100 patients, revealing a potential link between these antibodies and disease pathology.
• Establishment of a measurement system with accurate serological assays was conducted to facilitate more robust diagnostics.
• Findings may enhance early diagnosis and treatment approaches for autoimmune cerebellar ataxia, suggesting a need for clinical application.