Protocol for tailored in vitro neuronal networks on high-density microelectrode arrays with polydimethylsiloxane microstructures

Key Points

• Development of in vitro neuronal networks using high-density microelectrode arrays is crucial for neurobiological advancements.
• The approach utilizes polydimethylsiloxane microstructures to enhance the functionality of neuronal networks.
• This trial protocol aims to integrate tailored microelectrode arrays with specific neuronal characteristics for better research outcomes.
• If successful, this approach may redefine how neuronal activity is studied and understood, benefiting future neurological research.