Multi-cohort and single-cell profiling of aging genes reveals prognostic and therapeutic targets in breast cancer

Key Points

• Breast cancer outcomes relate significantly to identified aging genes, with implications for therapy.
• Aging genes serve as prognostic markers, impacting treatment plans and predictions for breast cancer progression.
• Multi-cohort and single-cell profiling approaches elucidated the critical role of aging genes in tumor biology.
• While findings are promising, external validation in broader cohorts is essential for clinical application.