Endometriosis: a polygenic & multifactorial syndrome

Key Points

• Endometriosis is a polygenic and multifactorial syndrome, exhibiting varying degrees of severity across individuals.
• Key evidence indicates that genetic predisposition and hormonal factors play crucial roles in its development and symptomatology.
• Analysis reveals a complex interplay of environmental, lifestyle factors, and genetic markers affecting endometriosis risk and manifestation.
• Understanding these mechanisms may enable more effective targeted treatments and interventions tailored to individual risks.

Abstract