Improvement in Health-Related Quality of Life in Adults With IBS-C Not Achieving Bowel Movement Frequency Criterion: Analysis of Two Phase 3 Plecanatide Trials | Synapse
March 3, 2026Open Access
Improvement in Health-Related Quality of Life in Adults With IBS-C Not Achieving Bowel Movement Frequency Criterion: Analysis of Two Phase 3 Plecanatide Trials
Key Points
Improvement in health-related quality of life was observed in adults with irritable bowel syndrome with constipation (IBS-C).
Participants in the plecanatide trials reported significant changes in bowel movement frequency and related symptoms.
Analysis included data from two phase 3 clinical trials focused on plecanatide's effectiveness for IBS-C patients.
Findings highlight the potential of plecanatide as a treatment option, though further studies may enhance understanding.