Noribogaine altered intrinsic properties of thalamocortical neurons in a sex-dependent manner

Key Points

• Noribogaine significantly alters intrinsic properties of thalamocortical neurons based on sex.
• The study reveals a distinct effect of noribogaine on neuronal properties in male and female models.
• Analysis was conducted using electrophysiological methods on thalamocortical neurons from both sexes.
• Findings imply that sex differences should be considered in developing treatments using noribogaine.