Plecanatide Is Efficacious in Women Aged 18 to 40 Years With IBS-C and Bloating: A Pooled Analysis of Two Phase 3, Randomized, Placebo-Controlled Trials | Synapse
March 3, 2026Open Access
Plecanatide Is Efficacious in Women Aged 18 to 40 Years With IBS-C and Bloating: A Pooled Analysis of Two Phase 3, Randomized, Placebo-Controlled Trials
Key Points
Plecanatide significantly reduces symptoms of bloating in women with IBS-C, improving their quality of life.
Participants experienced a notable decrease in symptom severity, with the treatment observed in a structured trial setting.
Randomized, placebo-controlled trials were conduct across two phases to evaluate plecanatide's efficacy.
These findings highlight the potential of plecanatide for treating specific IBS-C symptoms in younger women.