Dicranum scoparium extract modulates the NOX2/SOD2 axis and NF-κB signaling in a fibroblast-macrophage co-culture model

Key Points

• Nox2/Sod2 signaling modulation potentially reduces oxidative stress in the model.
• Key evidence includes observed changes in NF-κB signaling pathways.
• Observational analysis of fibroblast-macrophage co-cultures reveals significant interaction effects.
• Findings suggest a potential therapeutic target in oxidative stress-related diseases.