March 3, 2026Open Access

Impact of 18 FDG-avidity and immunosuppression on idiopathic and genetic cardiomyopathies

Key Points

Adverse heart failure outcomes are linked to 18 FDG-avidity in genotype-negative patients without clear inflammation.
Heart failure and arrhythmia outcomes were significantly worse for those with myocardial-only 18 FDG-avidity, suggesting a clinical concern.
Observational analysis highlights the role of 18 FDG uptake in identifying patients with potential adverse outcomes.
Immunosuppressive therapy does not appear to influence the disease progression, raising questions on its utility in these cases.

Abstract

Myocardial-only 18 FDG-avidity is only associated with adverse HF and arrhythmia outcomes in genotype-negative patients who do not clearly have CS. IST does not seem to modify the disease course, suggesting that not all myocardial 18 FDG uptake reflects clinically significant inflammation.

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Discussion

Authors

Shiva Tabaghi

Graham H. Bevan

Stephen Hankinson

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Institutions

University of Washington

Brigham and Women's Hospital

Oregon Health & Science University

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Impact of 18 FDG-avidity and immunosuppression on idiopathic and genetic cardiomyopathies

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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