Does area-level socioeconomic deprivation impact post-PCI outcomes stratified by P2Y12 inhibitor therapy?
Patients following percutaneous coronary intervention (PCI)
Clopidogrel or alternative P2Y12 inhibitor therapy, stratified by Area-Level Socioeconomic Deprivation Index (SDI)
Major adverse events (MAE) and bleedingcomposite
Higher socioeconomic deprivation is associated with worse ischemic outcomes with clopidogrel and worse bleeding outcomes with alternative P2Y12 inhibitors after PCI.
Higher SDI was associated with an increased risk of MAE with clopidogrel and bleeding with alternative therapy following PCI. Whether addressing socioeconomic disparities improves P2Y12 inhibitor-related outcomes remains to be determined.
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Jean G. Malavé
Cameron D. Thomas
Francesco Franchi
SHILAP Revista de lepidopterología
JACC Advances
University of North Carolina at Chapel Hill
University of Florida
Jacksonville University
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Malavé et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69a7600dc6e9836116a2c758 — DOI: https://doi.org/10.1016/j.jacadv.2025.102577