Rational Design of α-Glucosidase Inhibitor Peptides Derived from Goat (Capra hircus) Milk Casein

Key Points

• Peptide inhibitors effectively reduce alpha-glucosidase activity, improving glucose control in tested models.
• Key findings reveal a notable 30% decrease in enzyme activity with specific peptides from goat milk casein.
• The approach utilized peptide design strategies focused on optimizing inhibitors against alpha-glucosidase activity.
• Implications suggest possible future applications in diabetes treatment, requiring further validation in clinical settings.