Si-Miao-Yong-An decoction restores macrophage efferocytosis and modulates vascular inflammation via PPAR-γ/MerTK pathway to treat atherosclerosis

Key Points

• Efferocytosis improves significantly, leading to reduced inflammation and better vascular health.
• Key finding shows that macrophage function enhances with notable PPAR-γ/MerTK pathway activity.
• Analysis focuses on effective modulation strategies for atherosclerosis, particularly targeting vascular inflammation.
• Study highlights the importance of these pathways, indicating potential therapeutic options for atherosclerosis.