Thyroid hormone inactivation sustains cancer stem cell maintenance and tumorigenesis in basal cell carcinoma

Key Points

• Tumorigenesis occurs due to the maintenance of cancer stem cells influenced by thyroid hormone inactivation.
• Key evidence indicates that disrupting thyroid hormone activity significantly promotes cancer stem cell longevity and proliferation.
• The approach involves assessments of cellular growth in relation to hormonal changes and cancer development dynamics.
• These findings highlight the potential for targeting thyroid hormone pathways in developing novel therapeutic strategies against basal cell carcinoma.