Observation With or Without Subsequent Salvage Therapy for Pathologically Node-positive Prostate Cancer With Negative Conventional Imaging: Results From a Large Multicenter Cohort

Key Points

• Observation without salvage therapy led to varied outcomes in node-positive prostate cancer, underscoring the complexity of treatment decisions.
• In the cohort of pathologically node-positive prostate cancer cases, survival rates were notably influenced by subsequent salvage therapy, with implications for treatment pathways.
• Cohort study analyzing treatment approaches for prostate cancer highlighted the significant role of conventional imaging in therapy decisions and patient management.
• Findings suggest a need for further investigation into optimizing salvage therapy strategies, as results vary based on imaging outcomes.