High Dose Vitamin D As Prophylaxis Against Graft Vs Host Disease in Pediatric Hematopoietic Cell Transplant Recipients

Key Points

• High-dose vitamin D administration reduces the incidence of graft vs host disease in pediatric patients.
• A significant reduction of 30% in the occurrence of graft vs host disease was observed with vitamin D supplementation.
• Observational analysis across various pediatric transplant centers assessed immune responses to vitamin D.
• These findings suggest a possible preventive role for vitamin D in managing graft vs host disease risk.