A microfluidic spray drying approach for developing lipid nanoparticles dry powder via anti-solvent precipitation

Key Points

• Dry powder lipid nanoparticles were successfully developed using a microfluidic spray drying technique, enabling more efficient delivery systems.
• The technique utilizes anti-solvent precipitation, which enhanced nanoparticle stability and size distribution compared to traditional methods.
• Microfluidics allows precise control over formulation parameters, leading to optimized lipid nanoparticle characteristics.
• This innovative approach may improve drug delivery in therapeutic applications, warranting further investigations into performance.