From brain to eye: Annexin A1 and A2 as a key mediator of retinal neuroinflammation in Parkinson’s and Alzheimer’s disease

Key Points

• Annexin A1 and A2 are implicated in neuroinflammation of the retina, highlighting their significance in neurodegenerative diseases.
• Analysis reported increased levels of annexin proteins in retinal tissue from patients with Alzheimer’s and Parkinson’s disease.
• Observational analysis suggests these annexins could serve as biomarkers for disease progression in neurodegenerative disorders.
• Further investigation into annexin pathways may provide new approaches for treatment in Alzheimer's and Parkinson's diseases.