Plant-derived bioactive compounds modulate the gut microbiota in Alzheimer’s disease: Metabolite signaling, neuroimmune circuits, and systems-level regulation

Key Points

• Modulation of gut microbiota appears to influence neuroimmune circuits and metabolite signaling, enhancing brain health.
• Key evidence highlights that alterations in microbiota may be linked to cognitive function in Alzheimer's disease.
• Assessment of plant-derived bioactive compounds using systems-level regulation models indicates promising interactions with neuroimmune pathways.
• Significance supports further research on bioactive compounds and their role in modifying gut health in Alzheimer's disease.