FTO/SOCS6–m6A axis epigenetic modification links obesity to atopic dermatitis by regulating keratinocyte function

Key Points

• Obesity is significantly linked to atopic dermatitis through the FTO/SOCS6–m6A axis, impacting keratinocyte function.
• Key findings suggest a direct correlation observed in keratinocytes, highlighting m6A's role in this connection.
• The method involved analyzing the epigenetic modification pathways that regulate keratinocyte behavior associated with obesity.
• These findings may enable new treatment strategies for atopic dermatitis by targeting the identified epigenetic pathways.