ALC Kinetics Velocity and Acceleration Are Early Predictors of Non-Icans Neurotoxicities after Cilta-Cel Treatment

Key Points

• Neurotoxicities are predicted by ALC kinetics velocity and acceleration after cilta-cel treatment, showing significant early indicators.
• Velocity and acceleration metrics indicate notable changes in ALC kinetics within specific treatment timeframes.
• Observational analysis captures ALC kinetics metrics across multiple treatment phases, emphasizing the association with neurotoxicities.
• Highlights the need for early monitoring of ALC kinetics in managing potential neurotoxicities after cilta-cel treatment.