In-silico prediction of PCR inhibition mechanism and exploitation of bacterial EPS mediated calcium nanoparticles as PCR facilitator for efficient forensic DNA analysis

Key Points

• Enhanced forensic DNA analysis can be achieved with calcium nanoparticles that mitigate PCR inhibition.
• The study identifies key inhibition mechanisms linked to forensic DNA analysis using bacterial EPS.
• Assessment using computational predictions reveals bacterial EPS as a promising facilitator in PCR processes.
• The findings highlight the potential for improved outcomes in forensic applications, suggesting new avenues for research.