An adenovirus-vectored strategy expressing IFN-λ3 and IL-22 protects neonatal piglets from porcine epidemic diarrhea virus

Key Points

• Protection from porcine epidemic diarrhea virus was achieved in neonatal piglets after intervention.
• This strategy resulted in significant improvement in viral resistance, indicating enhanced protection.
• Observational analysis used an adenovirus vector expressing interferon-lambda3 and interleukin-22 in piglets.
• Findings highlight potential applications for improving viral defenses in young animals.