Low maternal folic acid during pregnancy exacerbates ectopic fat accumulation in the liver and muscle of male offspring

Key Points

• Ectopic fat accumulation is linked to maternal folic acid status in male offspring, indicating a crucial nutrient role.
• Adequate maternal plasma folic acid levels are vital for preventing metabolic health issues, especially in males.
• The analysis emphasizes the importance of maternal nutrition over mere dietary intake for offspring health.
• Findings highlight the need for awareness on maternal folic acid to improve male offspring metabolic outcomes.

Abstract