Poultry meat allergy is a rare condition that can present as a primary allergy or a secondary syndrome, such as the egg-bird syndrome. This syndrome involves primary sensitization to egg yolk (alpha-livetin (Gal d 5)) leading to cross-reactivity with poultry meat. We describe the case of a 12-year-old male patient who presented with a history of primary egg allergy and allergy to dog epithelium. He subsequently developed an allergy to poultry meat. Immunoallergological evaluation showed sensitization to egg yolk, chicken meat, and alpha-livetin (Gal d 5). Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) immunoblotting confirmed immunoglobulin E (IgE) reactivity to alpha-livetin and avian muscle serum albumin, with no cross-reactivity to dog epithelium. This confirmed the diagnosis of egg-bird syndrome. Due to severe asthma and multiple food allergies impacting his quality of life, the patient was treated with omalizumab. This case highlights the clinical complexity of the egg-bird syndrome and the utility of molecular diagnostics in differentiating cross-reactivities. Omalizumab proved effective in managing the patient's polysensitization and asthma, improving quality of life.
Building similarity graph...
Analyzing shared references across papers
Loading...
Dias et al. (Sun,) studied this question.
www.synapsesocial.com/papers/69a76587badf0bb9e87d96ec — DOI: https://doi.org/10.7759/cureus.102766
Marta I Dias
Rita S Pereira
Paulo R Santos
Cureus
Building similarity graph...
Analyzing shared references across papers
Loading...