Immunoinformatics-guided design of a universal chimeric multi-epitope subunit vaccine against Marburg virus disease and Ravn virus co-infection

Key Points

• The proposed multi-epitope vaccine demonstrates the potential to elicit robust immune responses against both Marburg and Ravn viruses.
• Key immunoinformatics techniques were employed to identify and design optimal epitopes for effective immune targeting.
• The novel chimeric vaccine approach may enhance protective outcomes against dual viral infections.
• This strategy holds promise for developing effective vaccines against multiple viral pathogens, emphasizing a need for further validation.