Tailoring of metal organic framework with electrospun polyacrylonitrile for on-chip electromembrane extraction and determination of anticancer drugs in biological samples

Key Points

• On-chip electromembrane extraction effectively isolates anticancer drugs from biological samples.
• A metal organic framework combined with electrospun polyacrylonitrile enhances extraction efficiency and accuracy.
• Evaluation demonstrated significant improvement in drug recovery rates and detection limits.
• This technique may enable more precise monitoring of drug concentrations in clinical settings.