Study design for an emulated trial of a 2 arm, parallel, stratified, adaptive, RCT of CABG versus PCI in people requiring myocardial revascularization at high risk (High-Risk REVASC)

Key Points

• CabG is compared to PCI for myocardial revascularization in high-risk patients, improving treatment options.
• The trial anticipates varying patient responses, utilizing an adaptive design to optimize outcomes.
• Adapted from standard models, the analysis facilitates evaluation of surgical strategies based on real-world data.
• Findings may inform clinical practices, enhancing treatment effectiveness for high-risk patients.

Abstract