Bioactive galloylquinic acids from Copaifera lucens as dual inhibitors of SARS-CoV-2 Spike and RdRp proteins

Key Points

• Inhibition of both spike protein and RdRp proteins indicates bioactive potential of galloylquinic acids, enhancing their therapeutic relevance.
• In vitro tests show that specific galloylquinic acids effectively reduce viral activity against SARS-CoV-2 with promising results.
• Analysis of molecular binding suggests that these natural compounds can effectively target key viral proteins involved in replication.
• The findings highlight the potential for developing new treatments based on plant-derived compounds, with further research needed.