A broadly protective antibody targeting gammaherpesvirus gB

Key Points

• Presence of a broadly protective antibody against gammaherpesvirus gB supports potential vaccine development.
• The antibody's efficacy was demonstrated in vivo, providing significant protection against infection.
• Observational analysis reveals the immune response activation by targeting gB, critical for clearing the virus.
• This discovery highlights the need for further investigation to evaluate potential vaccine applications.