Comparative value of retinal structural features versus systemic inflammatory and renal indicators in predicting short-term anti-VEGF response in diabetic macular edema: focus on OCT biomarkers

Key Points

• Baseline retinal integrity indicators significantly predict anti-VEGF response in DME, highlighting their clinical importance.
• The prediction model based on OCT analysis demonstrates strong discriminative capability, yet further validation is needed in larger cohorts.
• Observational analysis compared retinal structure with systemic inflammatory indicators using OCT biomarkers to determine effectiveness of treatment.
• Findings support the prioritization of OCT imaging for better management of diabetic macular edema in clinical settings.

Abstract