Live Imaging of Macrophage Cell Death During Mycobacterial Infection in Zebrafish Embryos

Key Points

• Macrophage lytic cell death is visualized using intravital microscopy, providing insights into immune responses.
• The imaging reveals dynamic processes in macrophages after Mycobacterium marinum infection, emphasizing the impact of infection.
• Assessment using intravital confocal microscopy allows direct observation of cellular events during infection.
• Understanding these mechanisms may help develop treatments for infections targeting similar immune responses.

Abstract