Binding activities of bisphenol analogues toward TTR and TBG and their potential to disrupt thyroid hormone homeostasis

Key Points

• Binding activities of bisphenol analogues affect thyroid hormone levels, leading to hormonal disruption.
• Key evidence shows significant binding to thyroxine and thyroxine-binding globulin, indicating potential interference.
• Analysis of binding interactions reveals that exposure to these chemicals could impact thyroid functionality.
• Findings suggest that increased exposure to bisphenol analogues may elevate health risks linked to thyroid disorders.