Diagnostic Accuracy of Cerebrospinal Fluid Presepsin vs. Procalcitonin in Post-Neurosurgical Bacterial Ventriculitis/Meningitis: A Machine Learning Analytical Approach

Key Points

• Presepsin demonstrates higher diagnostic accuracy than procalcitonin for bacterial meningitis.
• Findings indicate an accuracy of 92% for presepsin compared to 78% for procalcitonin in diagnosis.
• Assessment using machine learning analytical methods reveals significant differences in biomarker effectiveness.
• These results highlight the potential for improved diagnostic strategies in post-neurosurgical populations.