Injectable, regenerative and anti-infective PEGylated polyglycerol sebacate-modified calcium phosphate cements triggered by berberine and rhBMP-2 for oral bone defect repair

Key Points

• Calcium phosphate cements effectively promoted bone defect repair with 85% success rate over 3 months.
• Injectable formulations of pegylated polyglycerol showed reduced infection rates compared to standard options.
• Application involved using berberine and rhBMP-2, which enhanced regenerative capabilities significantly.
• This approach highlights the potential for improving oral bone repair interventions, suggesting further clinical exploration.