From flavones to flavanols: An enzymatic kinetic resolution approach to enantioenriched 2-(het)arylchroman-4-ols

Key Points

• Enzymatic resolution produces enantioenriched chroman-4-ols, enhancing compound diversity and application.
• Results demonstrate a notable enantioselectivity of 92% for the target flavanol compound in this approach.
• Analysis using kinetic resolution techniques allows for efficient synthesis of varied flavanols from flavones.
• Implications suggest potential for creating new flavanoid derivatives and improving pharmaceutical applications.