Mercaptophenylboronic acid-modified double-layer PEI-Au magnetic probes: an ultrasensitive SERS biosensor for broad-spectrum bacterial capture and specific detection in clinical urine samples

Key Points

• The biosensor achieves ultrasensitivity, effectively capturing a broad spectrum of bacteria from urine.
• With a detection capability in the picomolar range, it outperforms existing diagnostic methods.
• SERS technology combined with magnetic probes enhances the detection of targeted bacterial species.
• This tool may streamline clinical diagnostics, improving early bacterial infection detection in urine samples.