Comparative analysis of key phagocytic genes in humans and mice using machine learning integrated with single-cell RNA sequencing

Key Points

• Key phagocytic genes exhibit significant differences between humans and mice, indicating varied immune responses.
• Using machine learning models, accurate predictions of gene expression patterns were achieved with a 95% accuracy rate.
• Analysis incorporated single-cell RNA sequencing data to evaluate gene expression at a high resolution.
• This work suggests critical evolutionary differences in the immune systems of humans and mice.