Exploring the impact of IL-2 cytokine family on skin barrier function: pathophysiology and therapeutic strategies

Key Points

• Skin barrier function can be impaired by factors associated with the IL-2 cytokine family, leading to various skin disorders.
• Key evidence shows that alterations in IL-2 levels may correlate with a 30% increase in barrier permeability in certain conditions.
• Observational analysis highlights the links between IL-2 cytokines and skin pathophysiology, underpinning therapeutic approaches.
• Further research is necessary to validate these findings and to explore the potential for effective skin barrier therapies.