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Phosphorylation of the α subunit inhibits proteasome assembly and regulates cell cycle in an archaeon | Synapse
March 3, 2026
Phosphorylation of the α subunit inhibits proteasome assembly and regulates cell cycle in an archaeon
YW
Ya Wu
Qingdao Binhai University
QG
Qi Gan
Qingdao Binhai University
QG
Qi Gan
University of Georgia
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Puntos clave
Proteasome assembly is inhibited by phosphorylation of the α subunit, affecting the cell cycle.
The study reveals that phosphorylation plays a key regulatory role by impacting proteasome function.
Analysis shows the mechanism of phosphorylation’s effect on archaeal cell cycle control across various conditions.
Findings may enable future research on cell cycle regulation in other organisms, though specific mechanisms in archaea are spotlighted.
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Wu et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76775badf0bb9e87e0fd3
https://doi.org/https://doi.org/10.1016/j.cub.2026.01.021
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