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March 3, 2026Einstein (São Paulo)0 citationsOpen Access

Comment on: Multifocal papillary thyroid microcarcinomas: is the total tumor diameter associated with the tumor behavior? A retrospective cohort study

ISIlker SengulDŞDemet Kaya Şengül

Key Points

  • Total tumor diameter shows no significant association with tumor behavior, as highlighted in the comment.
  • Critiques reveal limitations in the findings of the referenced study, particularly regarding multifocal papillary thyroid carcinoma.
  • Retrospective cohort analysis was focused on multifocal papillary thyroid microcarcinomas to evaluate outcomes based on tumor diameter.
  • The comments emphasize the need for caution in interpreting results due to potential biases or confounding factors.

Abstract

Dear Editor, We write in reference to the recently conducted article, ‘Multifocal Papillary Thyroid Microcarcinomas: is the Total Tumor Diameter Associated with Tumor Behavior? A Retrospective Cohort Study,” by Nardi et al.() While the authors’ efforts are commendable, we feel it is necessary to critically assess some of their findings and limitations. The primary conclusion of the study suggests that total tumor diameter (TTD)—defined as the sum of the largest diameters of all tumor foci—shows no significant association with initial ...

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Cite This Study

Sengul et al. (2026) studied this question.

synapsesocial.com/papers/69a767babadf0bb9e87e21bdhttps://doi.org/10.31744/einstein_journal/2026ce2169
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