Farnesol induces apoptosis, LC3B/SQSTM1 mediated regulation of autophagy and downregulates anaerobic Glycolysis through suppression of LDH and PKM in A549 lung adenocarcinoma cells

Key Points

• Farnesol induces apoptosis in A549 lung adenocarcinoma cells, leading to cell death.
• Key metrics include downregulation of LDH and PKM, which are critical in glycolysis.
• Assessment of autophagy highlights the role of LC3B and SQSTM1 in cellular processes.
• Results indicate that targeting these pathways may enhance cancer treatment efficacy.