Asiatic acid promotes CD8+ T cell-mediated antitumor immunity by targeting HDAC8/CXCL10 axis in hepatocellular carcinoma

Key Points

• Asiatic acid promotes enhanced CD8+ T cell-mediated antitumor immunity.
• The investigation highlights a significant increase in CXCL10 levels after treatment with asiatic acid.
• Assessment using a target approach revealed the involvement of the HDAC8 pathway.
• The findings support further exploration of asiatic acid as a therapeutic option for hepatocellular carcinoma.