Synergistic dissolving microneedle-tranexamic acid nanofibrous patch as a dual-phase delivery system for sustained release in melasma therapy

Key Points

• Melasma therapy shows improved outcomes with sustained release using a microneedle system—indicating enhanced treatment efficacy.
• Key evidence demonstrates the application of tranexamic acid in a novel nanofibrous patch for effective delivery.
• Analysis of the microneedle-tranexamic acid patch supports dual-phase delivery methods in dermatological applications.
• This highlights the potential for further development in melasma treatment applications, necessitating clinical trials.