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Synapse
March 3, 20260 citations

The Application of a Formulation Containing Hydroxypropyl Tetrahydropyrantriol and Niacinamide to Augment Anti-aging Benefits in a Double-blind, Randomized Nonablative Laser Treatment Study.

GAGlynis AblonJPJyotsna PaturiFJFranck Juchaux

Key Points

  • Augmented skin resurfacing benefits were observed with HPT/NAM use post-treatment.
  • The healing benefits observed were comparable to clinical control methods during the study.
  • Double-blind randomized methods ensured reliable results in evaluating skin treatment efficacy.
  • Findings indicate potential for improved anti-aging effects, meriting further exploration in dermatologic applications.

Abstract

This study demonstrated comparable healing benefits to the clinical control along with augmented skin resurfacing benefits with HPT/NAM use following a nonablative fractional laser treatment.

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Cite This Study

Ablon et al. (2025) studied this question.

synapsesocial.com/papers/69a7684abadf0bb9e87e4430
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Review of Post-laser-resurfacing Topical Agents for Improved Healing and Cosmesis.2021 · 18 citations
  2. 2Transglutaminases in skin epidermis.2006 · 133 citations
  3. 3Nonablative Fractional Laser Resurfacing in Skin of Color: Evidence-based Review.2017 · 65 citations
  4. 4Effect of a Tranexamic Acid, Kojic Acid, and Niacinamide Containing Serum on Facial Dyschromia: A Clinical Evaluation2019 · 66 citations
  5. 5Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing.1990 · 1,186 citations