In silico discovery of a novel sheep whey protein-derived antimicrobial peptide: antimicrobial activity, mechanism of action, and application

Key Points

• The antimicrobial peptide demonstrates significant activity against several bacterial strains, enhancing potential clinical use.
• Key evidence highlights a 75% reduction in bacterial growth in vitro, emphasizing its efficacy.
• Utilizing in silico methods, the study explores the peptide's mechanism of action, revealing its interaction with bacterial membranes.
• The findings support the peptide's potential application in food preservation or clinical settings, though further validation is necessary.