Protein Neddylation Beyond Tumor Cells is a Vital Modulator of Anticancer Immunity

Key Points

• Anticancer immunity is significantly modulated by neddylation outside tumor cells, impacting immune response.
• Key findings show that alterations in neddylation influence immune behavior and tumor interaction.
• Analysis of the tumor microenvironment indicates that neddylation affects immune cell function and activity.
• Understanding neddylation enhances therapeutic strategies; further exploration is needed in various cancer contexts.