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March 4, 2026Journal of Turkish Society of Obstetric and Gynecology0 citationsOpen Access

Differential expression of c-kit, E-cadherin, and beta-catenin in endometriosis and normal endometrial tissue

EAEsra Ayhan AtasayarFŞFatih ŞendağGSGürdenız Serın

Key Points

  • To investigate the expression levels of c-kit, E-cadherin, and beta-catenin in endometriosis compared to normal endometrial tissue.
  • Analyzed expression levels of c-kit, E-cadherin, and beta-catenin in endometriosis and normal endometrium.
  • Used tissue samples from affected and unaffected sites.
  • Increased expression of c-kit in endometriosis samples compared to normal tissue.
  • Reduced expression of beta-catenin in endometriosis samples.
  • No significant difference in E-cadherin expression between endometriosis and normal samples.

Abstract

Increased c-kit expression, along with reduced beta-catenin expression in endometriosis samples, suggests that these molecules contribute to endometriosis pathogenesis. However, because no significant difference was found in E-cadherin expression, a definitive conclusion cannot be made regarding the involvement of E-cadherin in endometriosis development.

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Cite This Study

Atasayar et al. (2026) studied this question.

synapsesocial.com/papers/69a7ccb2d48f933b5eed8690https://doi.org/10.4274/tjod.galenos.2026.53358
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