PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
March 4, 2026Journal of Clinical Oncology

Prostate cancer in patients with HIV: A multisite retrospective cohort study.

View Full Paper
Ask AI
Bookmark
Share

Authors

FWF WardropSKSam Hyun KwonMKMatthew Klein

Discussion

Loading...

Member takes

Overview

Retrospective cohort study reveals lower survival in HIV-positive men with prostate cancer, indicating critical care needs.

Key Points

  • This study aims to characterize demographics and survival outcomes of prostate cancer in patients with HIV.
  • Retrospective cohort study using de-identified electronic health records
  • Analysis of men aged 18 to 90 diagnosed with prostate cancer, stratified by HIV status
  • Exclusion of patients with another malignancy within one year, except non-melanoma skin cancer
  • Utilized propensity score matching, Chi-square tests, Kaplan-Meier survival analysis, and Cox proportional hazards models.
  • Among 625,752 patients, 1,645 were diagnosed with prostate cancer and HIV
  • PLWH were younger at diagnosis (mean age 62) compared to non-HIV cohort (mean age 67)
  • Higher prevalence of comorbid conditions in PLWH, including diabetes, hypertension, and obesity
  • After matching, 3-year survival was significantly lower for PLWH (p < 0.05)

Cite This Study

Wardrop et al. (2026) studied this question.

synapsesocial.com/papers/69a7ccf7d48f933b5eed8e76https://doi.org/10.1200/jco.2026.44.7_suppl.326
View Full Paper
Ask AI
Bookmark
Share